Premium 2,5-Hexanedione (CAS 110-13-4) don haɗakar Magunguna & Polymer

Sunan sinadarai: 2,5-Hexanedione

Ma'anar kalmomi: Hexan-2,5-Dion; hexane-2,5-dione; Acetonylacetone

Nauyin kwayoyin halitta:C₆H₁₀ABINCI₂

Bayyanar: Ruwa mai launin ruwan kasa mai haske

Kwanciyar hankali: 1. Kada a taɓa shi da sinadarai masu ƙarfi, sinadarai masu rage ƙarfi, da kuma alkali mai ƙarfi. Ruwan yana da yawa, tururin yana da ƙasa, kuma yawanci yana da aminci a yi amfani da shi a yanayi na yau da kullun, amma har yanzu yana da mahimmanci a kula da hana gobara. Ana iya mirgine shi da ruwa, ethanol da ether, amma ba tare da hydrocarbon solvents ba. Hakanan ba ya narkewa a cikin sinadarin potassium hydroxide ko potassium carbonate. Yana iya narkar da polymethyl methacrylate, polystyrene, polyvinyl acetate, vinyl chloride da vinyl acetate copolymer, cellulose nitrate, phenolic resin da sauran resins na roba da kuma rosin, conch rosin, mai da sauran resins na halitta. Yana iya narkar da wani ɓangare na shellac, dewaxed dama resin, glycerin trirosin ester, man auduga, da sauransu.

2. Halayen Sinadarai: Halayen ketones gabaɗaya. Yana yin aiki tare da diphosphorus pentasulfide don samar da 2, 5-dimethylthiophene. Ana samar da 2, 5-dimethylpyrrole lokacin da aka yi aiki tare da maganin alcohol-ammonia ko kuma aka dumama shi da ammonium carbonate. Rashin ruwa yana samar da 2, 5-dimethylfuran. Yana yin aiki tare da 2, 4-dinitrophenylhydrazine don samar da bis (2, 4-dinitrophenyl) hydrazone tare da wurin narkewa na 257 ° C.

3. Yana samuwa a cikin ganyen taba da aka warkar da hayaki da hayaki.

4. Matsakaici mai motsa jiki na gida, yawan maida hankali yana haifar da maganin sa barci.

2,5-Hexanedione yana aiki a matsayin tubalin gini mai amfani da yawa kuma babban abin da ke haifar da haɗakar magunguna na zamani. Tsarin diketone mai daidaituwa, wanda ke ɗauke da ƙungiyoyin carbonyl guda biyu masu amsawa, ya sa ya zama muhimmin matsakaici don gina hadaddun mahaɗan heterocyclic da cyclic waɗanda ke tsakiya ga yawancin sinadaran magunguna masu aiki (APIs).

Babban aikace-aikacensa na magunguna sun haɗa da:

Haɗakar Scaffolds na Heterocyclic: 2,5-Hexanedione ana amfani da shi sosai a cikin haɗakar Paal-Knorr don samar da furan da pyrroles da aka maye gurbinsu. Waɗannan zoben heterocyclic masu mambobi biyar sifofi ne na musamman a cikin ilmin sunadarai na magani, suna samar da tushen magunguna da yawa tare da ayyukan halittu daban-daban (misali, maganin rigakafi, maganin kumburi, hana kinase).

Samar da Abubuwan Da Suka Samu Daga Pyrrole: Ta hanyar daskare sinadarin amine na farko, 2,5-Hexanedione yana samar da 2,5-dimethylpyrrole da abubuwan da suka samo asali daga gare shi yadda ya kamata. Waɗannan pyrroles su ne manyan hanyoyin da za a iya ƙara aiki a cikin ƙwayoyin halitta masu rikitarwa da ake amfani da su a binciken magunguna da haɓaka su.

Abin da ke Gabatar da Haɗaɗɗun Zagaye: Haɗaɗɗen zai iya fuskantar halayen ƙwayoyin halitta don samar da abubuwan da suka samo asali daga cyclohexenone, waɗanda suke da mahimmanci don haɗa tsarin steroid da sauran tsarin zagaye masu dacewa da magunguna.

Matsakaici ga Sinadaran Musamman: Yana aiki a matsayin kayan farawa wajen haɗa sinadarai masu ci gaba waɗanda aka haɗa su cikin magungunan ƙarshe waɗanda ke niyya ga fannoni daban-daban na magani, gami da cututtukan tsarin jijiyoyi na tsakiya (CNS) da cututtuka masu yaɗuwa.

Saboda rawar da take takawa a cikin waɗannan muhimman hanyoyin roba, an ƙayyade 2,5-Hexanedione a cikin hanyoyin kera magunguna na APIs na gama gari da sabbin magunguna na bincike. Matsayinmu mai tsarki (>99%) yana tabbatar da daidaito, ƙarancin bayanan ƙazanta, da kuma bin ƙa'idodin inganci masu tsauri da ake buƙata don kera magunguna na GMP, yana tallafawa haɓaka inganci daga bincike zuwa samar da kayayyaki na kasuwanci.

1. Tsarkakakken ruwa mai zurfi 99.0% min

2. Yi amfani da ɗanɗano iri-iri.

3. Muna da takardar shaidar ISO 9001, ISO 14001 da ISO22000, muna kuma da takardar shaidar HACCP, muna da takardar shaidar Halal da kosher ta wannan samfurin.

5. Muna da babban ƙarfin aiki, don haka, yawanci muna da lokacin jagora mai sauri.

6. Za mu iya bayar da samfurin kyauta daga 10g zuwa 50g don gwajin dakin gwaje-gwajenku. Yawancin lokaci muna isar da samfurin ta hanyar jigilar kaya ta ƙasashen waje kamar DHL ko Fedex. Yana da sauri kuma mai sauƙi.

1. Samfurin da aka yi amfani da shi shine 20g/30g/50g a kowace kwalba.

2. Ƙaramin marufin shine 1kg /5kg /10kg a kowace kwalba.

3.25 kg a kowace ganga (Dangon filastik mai daraja a abinci, ba tare da filastik ba, rahoton takardar shaida na ɓangare na uku)

Ana iya keɓance marufi gwargwadon buƙatun abokin ciniki